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MYP_129325
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Basic Information
Beta-defensin
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
123 amino acids
C588H956N168O185S9
Standard
Sequence
MKLLLLALPVLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCVPSNEDHRRVPMTSPTPLSDSTPGIIDDILTVRFTTDYFEVSSKKDMVEESEAGRGTETSLPNVHHSS
Physicochemical Analysis
13627.48 Da
6.88
-0.19
-0.73
-0.0015
-0.42
0.64
-0.08
52.62
78.37
0.0407
8480.00
8855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
5653.03
-62.82
201.0
198.0
450.0
950.0
19.0
128.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0052342 VERIFIED: NO
Provenance & Taxonomy
Pan troglodytes [Animal]
Defensin
9598
Structure & Mods
linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A2J8PZ41/entry
RECORD: Rec_0095069 VERIFIED: NO
Provenance & Taxonomy
Pan troglodytes [Animal]
Beta-defensin; Defensin
9598
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/
RECORD: Rec_0178035 VERIFIED: NO
Provenance & Taxonomy
Pan troglodytes [Animal]
Beta-defensin; Defensin
9598
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Bacillus subtilis
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/
RECORD: Rec_0230730 VERIFIED: NO
Provenance & Taxonomy
Pan troglodytes [Animal]
Beta-defensin; Defensin
9598
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/
RECORD: Rec_0239146 VERIFIED: NO
Provenance & Taxonomy
Pan troglodytes [Animal]
Beta-defensin; Defensin
9598
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Salmonella Typhimurium
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/
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