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MYP_129324
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Basic Information
L10, 11-DPS3 (Derived from dermaseptin-PS3 (DPS3))
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
23 amino acids
C122H206N32O33
Standard
Sequence
ALWKDILKNLLKAALNEINQIVQ
Physicochemical Analysis
2649.14 Da
8.54
0.80
0.60
0.0346
0.22
0.72
0.13
22.26
161.30
0.0435
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1087.42
-6.24
35.0
34.0
93.0
187.0
2.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0201541 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse blood cells
50 μM
Hemolysis
PMID30087268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30087268/
RECORD: Rec_0295835 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans (NCYC 1467)
16 μM
MIC
PMID30087268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30087268/
RECORD: Rec_0316358 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PMID30087268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30087268/
RECORD: Rec_0335128 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli (NCTC 10418)
16 μM
MIC
PMID30087268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30087268/
RECORD: Rec_0345964 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
horse red blood cells
PMID30087268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30087268/
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