Peptide Database

Peptide NameAntimicrobial peptide 2 (AamAP2) (Non-disulfide-bridged peptide 4.12) (NDBP-4.12)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC389H635N107O104S2

DescriptionStandard

        MEIKYLLTVFLVLLIVSDHCQAFPFSLIPHAIGGLISAIKGRRKRDLDGQIDRSRNFRKRDAELEELLSKLPIY
    

Molecular Weight8538.99 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)2.67

Net Charge (pH 7.4) 2.32

Charge Density (pH 7.0) 0.0361

GRAVY Index0.05

Hydrophobic Moment 0.48

Boman Index0.01

Instability Index42.91

Aliphatic Index 122.57

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3408.82

LogP -23.65

H-bond Donors 121.0

H-bond Acceptors 111.0

Rotatable Bonds 291.0

Heavy Atoms 602.0

Ring Count 11.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049690 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus amoreuxi [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0117860 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus amoreuxi [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetCandida albicans

RECORD: Rec_0303645 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus amoreuxi [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli (Gram-negative)