Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC213H342N58O77S5

DescriptionStandard

        MEKILDLDVQVKAQKESNDSSGDERITSFSLCTPGCAKTGSFNSYCC
    

Molecular Weight5107.66 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.0539

GRAVY Index-0.44

Hydrophobic Moment 0.42

Boman Index-0.08

Instability Index27.29

Aliphatic Index 58.09

Aromaticity 0.0638

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2215.10

LogP -29.77

H-bond Donors 80.0

H-bond Acceptors 80.0

Rotatable Bonds 174.0

Heavy Atoms 353.0

Ring Count 4.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0123846 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus hyicus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria