Peptide Database

Peptide NamePomc (141-162)

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC121H184N32O36

DescriptionStandard

        RRPVKVYPNVAENESAEAFPLEF
    

Molecular Weight2662.95 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0535

GRAVY Index-0.58

Hydrophobic Moment 0.65

Boman Index-0.09

Instability Index65.11

Aliphatic Index 67.83

Aromaticity 0.1304

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1102.81

LogP -9.05

H-bond Donors 36.0

H-bond Acceptors 35.0

Rotatable Bonds 82.0

Heavy Atoms 189.0

Ring Count 6.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0302985 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetGPR68 (Human)

Activity1290 nM

MethodEC50