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MYP_129274
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Basic Information
L6A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C136H224N36O34
Standard
Sequence
KWKSFAKTFKSAKKTVLHTALKAISS
Physicochemical Analysis
2907.45 Da
10.78
6.84
6.58
0.2631
-0.29
0.65
-0.06
9.82
71.54
0.1154
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1159.04
-10.42
43.0
42.0
101.0
206.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0140107 VERIFIED: YES
Provenance & Taxonomy
PeptideV13K [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
B16
62.5 μM
IC50
PaperPubMed PMID: 21252288 PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0148193 VERIFIED: YES
Provenance & Taxonomy
PeptideV13K [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
62.3 μM
IC50
PaperPubMed PMID: 21252288 PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0171020 VERIFIED: YES
Provenance & Taxonomy
PeptideV13K [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 21252288 PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0177431 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PeptideV13K
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
RD
>83.6 μM
IC50
PaperStudies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structural framework PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0189509 VERIFIED: YES
Provenance & Taxonomy
PeptideV13K [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
A-375
58.7 μM
IC50
PaperPubMed PMID: 21252288 PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
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