Peptide Database

Peptide NameCholecystokinin-58 desnonopeptide

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC230H387N79O72S

DescriptionStandard

        VSQRTDGESRAHLGALLARYIQQARKAPSGRMSIVKNLQNLDPSHRISD
    

Molecular Weight5443.08 Da

Isoelectric Point (pI)10.83

Net Charge (pH 7.0)3.91

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.0799

GRAVY Index-0.73

Hydrophobic Moment 0.67

Boman Index-0.23

Instability Index44.07

Aliphatic Index 85.71

Aromaticity 0.0204

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2492.92

LogP -31.74

H-bond Donors 88.0

H-bond Acceptors 79.0

Rotatable Bonds 186.0

Heavy Atoms 382.0

Ring Count 5.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101165 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCholecystokinin-58 desnonopeptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation

TargetCCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0207182 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCholecystokinin-58 desnonopeptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0218512 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 36.7%, E 0.0%, T 38.8%, C 24.5% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0265645 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGastrin/cholecystokinin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide