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MYP_129257
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Basic Information
Antimicrobial peptide AcrAP1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C97H149N21O22
Standard
Sequence
FLFSLIPHAISGLISAFK
Physicochemical Analysis
1961.35 Da
8.76
0.85
0.59
0.0470
1.41
0.46
0.57
-0.51
141.11
0.1667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
664.62
-2.11
23.0
24.0
61.0
140.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156859 VERIFIED: YES
Provenance & Taxonomy
Androctonus crassicauda [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
16 μM
MIC
PMID25332684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25332684/
RECORD: Rec_0254217 VERIFIED: YES
Provenance & Taxonomy
Androctonus crassicauda [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
250 μM
MIC
PMID25332684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25332684/
RECORD: Rec_0254556 VERIFIED: YES
Provenance & Taxonomy
Androctonus crassicauda [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
PaperPubMed PMID: 25332684 PMID25332684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25332684/
RECORD: Rec_0276629 VERIFIED: YES
Provenance & Taxonomy
Androctonus crassicauda [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
albicans
16 μM
MIC
PaperPubMed PMID: 25332684 PMID25332684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25332684/
RECORD: Rec_0277162 VERIFIED: YES
Provenance & Taxonomy
Androctonus crassicauda [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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