Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length164 amino acids

Chemical FormulaC821H1323N237O240S7

DescriptionStandard

        MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLSAAKSELDKAIGRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVIATFRTGTWDAYKNL
    

Molecular Weight18578.19 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)7.58

Net Charge (pH 7.4) 7.24

Charge Density (pH 7.0) 0.0462

GRAVY Index-0.38

Hydrophobic Moment 0.71

Boman Index-0.08

Instability Index37.16

Aliphatic Index 87.50

Aromaticity 0.0854

Extinction Coeff. Reduced 25440.00

Extinction Coeff. Oxidized 25565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7825.39

LogP -76.92

H-bond Donors 277.0

H-bond Acceptors 256.0

Rotatable Bonds 634.0

Heavy Atoms 1305.0

Ring Count 21.0

Amide Bonds 179.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239394 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage VEc74 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic