Peptide Database

Peptide NameDermaseptin cDNA

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC384H636N102O123S4

DescriptionStandard

        MDILKKSLFLVLFLGLVSLSICEEEKRENEDEEKQEDDEQSEMKRALWKTMLKKLGTVALHAGKAALGAVADTISQGAQ
    

Molecular Weight8778.03 Da

Isoelectric Point (pI)4.93

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.71

Charge Density (pH 7.0) -0.0557

GRAVY Index-0.28

Hydrophobic Moment 0.53

Boman Index-0.03

Instability Index48.62

Aliphatic Index 98.86

Aromaticity 0.0380

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3672.36

LogP -33.04

H-bond Donors 126.0

H-bond Acceptors 124.0

Rotatable Bonds 315.0

Heavy Atoms 613.0

Ring Count 5.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375994 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Bacterium]

FamilyFrog skin active peptide (FSAP) family; Dermaseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal