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MYP_129168
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Basic Information
HCV gp (710-725)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C101H152N18O21
Standard
Sequence
VSFAIKWEYVLLLFLL
Physicochemical Analysis
1954.40 Da
5.97
-0.27
-0.48
-0.0166
1.81
0.23
0.66
4.07
188.75
0.2500
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
619.39
3.42
22.0
21.0
61.0
140.0
5.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005693 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV) PsV
PMID20156485 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20156485/
RECORD: Rec_0044182 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Entry inhibition
Hepatitis C virus(HCVpp) | hepatoma cells
0.3±0.4 μM
EC50
Mammalian: 100 h; Yeast: >20 h; E. coli: >10 h
PaperA peptide derived from hepatitis C virus E2 envelope protein inhibits a post-binding step in HCV entry. | Liu R, Tewari M, Kong R, Zhang R, Ingravallo P, Ralston R. | Antiviral Res. 2010 May;86(2):172-9. | DOI:10.1016/j.antiviral.2010.02.316 | PMID:20156485 PMID20156485 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20156485/
RECORD: Rec_0060477 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Vesicular Stomatitis Virus (VSV) PsV
PMID20156485 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20156485/
RECORD: Rec_0082653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 20156485 PMID20156485 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20156485/
RECORD: Rec_0087980 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of virus infection in primary human hepatocytes
0.3 μM
EC50
PaperPubMed PMID: 20156485 PMID20156485 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20156485/
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