Peptide Database

Peptide NameTagraxofusp

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length524 amino acids

Chemical FormulaC2553H4026N692O798S16

DescriptionStandard

        MGADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYEYMAQACAGNRVRRSVGSSLSCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAGANYAAWAVNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIALSSLMVAQAIPLVGELVDIGFAAYNFVESIINLFQVVHNSYNRPAYSPGHKTRPHMAPMTQTTSLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF
    

Molecular Weight57694.47 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-12.41

Net Charge (pH 7.4) -13.45

Charge Density (pH 7.0) -0.0237

GRAVY Index-0.34

Hydrophobic Moment 0.86

Boman Index0.02

Instability Index40.59

Aliphatic Index 84.52

Aromaticity 0.0744

Extinction Coeff. Reduced 56840.00

Extinction Coeff. Oxidized 57090.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049922 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyInterferon

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory

Half-LifeThe reported half-life of tagraxofusp is of around 51 minutes.[L4897]

RECORD: Rec_0300159 VERIFIED: NO