Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length504 amino acids

Chemical FormulaC2476H4041N679O702S31

DescriptionStandard

        MVTILLSATLNPGVQVKLTQKGLDYARQVGMEKLKQKLQTIQIPDFSGKSKVKYSLTNVRIVGMGIPNSALTLAPGTGISMSIRDAFINVRGNWRVRYKFIRTSGSFDLDVNGLSIGTTISVTSGAGGRPVVSSVNCGASIGSTRIKFHGRASWLYNIFRKLIEREKALIWCISVLLVLQICPRVSDTVSDLNPRLQTLNVLARVDKHAEIEYSMVSSPVVTQSSIALNLKGQFYNIGRHQEPPFSPQPFSMPTQQHMVYMGMSAFTANSAGFVYNRAGILSVSITDDMIPSVSPIRLSTSSFGVIIPEISRRFPGLKMKLTMSAASDPMVIFKPNNMTITAVATVTAFAIQADSTLSPLFVLKLDTSVSAAMSVTQMRLGGTLSLNKMEMSVQSSNVGNFQVSVLNNFIPTVLRWVVIPIVNTELRKGYPLPELQNMQLMNTQLQIMQVRISLCSVNFYVCVCVCVCVCVLITVLIIRQERWCIRATVERKKNYRARGELVIL
    

Molecular Weight55547.71 Da

Isoelectric Point (pI)9.96

Net Charge (pH 7.0)25.77

Net Charge (pH 7.4) 25.12

Charge Density (pH 7.0) 0.0511

GRAVY Index0.24

Hydrophobic Moment 0.75

Boman Index0.12

Instability Index34.84

Aliphatic Index 103.95

Aromaticity 0.0694

Extinction Coeff. Reduced 43890.00

Extinction Coeff. Oxidized 44515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0196761 VERIFIED: NO

Provenance & Taxonomy

OrganismMyripristis murdjan [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria