Peptide Database

Peptide NameBeta-defensin 128 (Beta-defensin 28, DEFB-28; Defensin, beta 128; Human, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC381H620N106O107S6

DescriptionStandard

        ARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEKKHVSFKKPHQHSGEKLSVLQDYIILPTITIFTV
    

Molecular Weight8590.03 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)7.00

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.0934

GRAVY Index-0.45

Hydrophobic Moment 0.60

Boman Index-0.11

Instability Index20.55

Aliphatic Index 79.20

Aromaticity 0.0800

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3476.41

LogP -31.43

H-bond Donors 127.0

H-bond Acceptors 123.0

Rotatable Bonds 298.0

Heavy Atoms 600.0

Ring Count 11.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053079 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0288994 VERIFIED: NO