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MYP_129149
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Basic Information
SVS-2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C97H182N26O20
Standard
Sequence
KVKVKVKVPPTKVKVKVK
Physicochemical Analysis
2032.64 Da
10.85
7.75
7.54
0.4307
-0.32
0.14
-0.24
-11.77
112.78
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
768.83
-3.34
26.0
28.0
73.0
143.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016052 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
k=D-Lys; v=D-Val; p=D-Pro; t=D-Thr
Bio-Activity Profile
Antimicrobial Anticancer
KB
4.5±0.5 μM
IC50
PaperPubMed PMID: 22413859 PMID22413859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22413859/
RECORD: Rec_0022317 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
p=D-Pro
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-436
5.6±0.5 μM
IC50
PaperPubMed PMID: 22413859 PMID22413859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22413859/
RECORD: Rec_0048515 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
A-549
3.2±0.6 μM
IC50
PMID22413859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22413859/
RECORD: Rec_0054027 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
k=D-Lys; v=D-Val; p=D-Pro; t=D-Thr
Bio-Activity Profile
Antimicrobial Anticancer
A549
3.2±0.6 μM
IC50
PaperPubMed PMID: 22413859 PMID22413859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22413859/
RECORD: Rec_0075092 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
p=D-Pro
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
50 %
Hemolysis
PaperPubMed PMID: 22413859 PMID22413859 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22413859/
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