MYP_129099
Peptide 207
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Standard
7 amino acids
C62H78N20O8
Standard
WWRRWWR
1231.41 Da
12.00
2.76
2.56
0.3943
-2.44
1.10
-0.62
172.23
0.00
0.5714
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
486.78
0.99
21.0
11.0
33.0
90.0
8.0
6.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0009267
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Candida albicans
29.04292615 μM
MIC
RECORD: Rec_0012582
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
The Ⓧ (position: 2 and 6) in sequence indicate (S)-4-pentenyl alanine. Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling through an oct-4-enyl hydrocarbon staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus aureus ATCC 25923
56±12 μg/mL
MIC
RECORD: Rec_0130334
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
horse RBCs
Hemolysis
RECORD: Rec_0262804
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Pseudomonas aeruginosa
62.65028719 μM
MIC
RECORD: Rec_0268482
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Methicillin-resistant Staphylococcus aureus (MRSA)
100 μg/mL
MIC
Showing 5 records on this page · Page 1 of 2