Peptide Database

Peptide NameBrevinin-1CG3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC357H597N97O108S4

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDDSDKRDVEVEKRFLSTLLNVASNVVPTLICKITKKC
    

Molecular Weight8104.40 Da

Isoelectric Point (pI)7.69

Net Charge (pH 7.0)0.49

Net Charge (pH 7.4) 0.20

Charge Density (pH 7.0) 0.0070

GRAVY Index-0.16

Hydrophobic Moment 0.64

Boman Index-0.10

Instability Index44.59

Aliphatic Index 107.14

Aromaticity 0.0571

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3382.12

LogP -30.68

H-bond Donors 121.0

H-bond Acceptors 113.0

Rotatable Bonds 285.0

Heavy Atoms 566.0

Ring Count 5.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004364 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops chunganensis [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Antifungal Fungicide Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence