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MYP_129070
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Basic Information
TL-2 (Derived from Temporin-2Tl (TL))
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C92H136N26O15
Standard
Sequence
FVRWWSKWLRRIL
Physicochemical Analysis
1846.23 Da
12.00
3.76
3.55
0.2892
-0.14
0.98
-0.08
136.48
112.31
0.3077
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
691.84
0.34
28.0
19.0
57.0
133.0
7.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0217308 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria: Bacillus subtilis (KCTC 3068)
4 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0221587 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa (KCTC 1637)
8 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0225948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0319743 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative bacteria: Escherichia coli (KCTC 1682)
8 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
RECORD: Rec_0336757 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (KCTC 1621)
2 μM
MIC
PMID26311041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26311041/
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