Peptide Database

Peptide NameMetastasis-suppressor KiSS-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC525H845N173O152S4

DescriptionStandard

        EPLAKMAPVVNPEPTGQQSGPQELVNAWQKGPRYAESKPGAAGLRARRTSPCPPVENPTGHQRPPCATRSRLIPAPRGSVLVQREKDMSAYNWNSFGLRYGRRQVARAARG
    

Molecular Weight12140.65 Da

Isoelectric Point (pI)11.09

Net Charge (pH 7.0)10.91

Net Charge (pH 7.4) 10.64

Charge Density (pH 7.0) 0.0983

GRAVY Index-0.89

Hydrophobic Moment 0.74

Boman Index-0.21

Instability Index65.39

Aliphatic Index 54.59

Aromaticity 0.0541

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5224.81

LogP -63.76

H-bond Donors 181.0

H-bond Acceptors 168.0

Rotatable Bonds 383.0

Heavy Atoms 854.0

Ring Count 24.0

Amide Bonds 122.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0084386 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyKISS1

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsTyr91 Phosphotyrosine; Tyr100 Amidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide