Peptide Database

Peptide NameGI-20W17

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC116H195N35O27

DescriptionStandard

        GIKEWKRIVQRIKDFLRNLV
    

Molecular Weight2512.01 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1880

GRAVY Index-0.41

Hydrophobic Moment 0.97

Boman Index-0.22

Instability Index13.34

Aliphatic Index 126.50

Aromaticity 0.1000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1056.55

LogP -5.59

H-bond Donors 38.0

H-bond Acceptors 31.0

Rotatable Bonds 89.0

Heavy Atoms 178.0

Ring Count 3.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381960 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targeted Human Immunodeficiency Virus Type 1 HIV-1

Activity7.4 μM

MethodEC50

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