Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC225H378N60O76S4

DescriptionStandard

        MKNSKELISEVIEEVSEKELKEIAGGKKGSGWVRTITDDCPNSIIVCC
    

Molecular Weight5268.02 Da

Isoelectric Point (pI)4.93

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.0524

GRAVY Index-0.28

Hydrophobic Moment 0.59

Boman Index-0.03

Instability Index38.09

Aliphatic Index 91.25

Aromaticity 0.0208

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2219.53

LogP -22.99

H-bond Donors 79.0

H-bond Acceptors 78.0

Rotatable Bonds 186.0

Heavy Atoms 365.0

Ring Count 3.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205848 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus gallolyticus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria