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MYP_129038
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Basic Information
BF2d
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C115H196N44O29S
Standard
Sequence
TRSSRAGLQWPVGRVHRLLRKGGC
Physicochemical Analysis
2691.13 Da
12.00
5.47
5.22
0.2281
-0.64
0.83
-0.28
71.64
77.08
0.0417
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1207.60
-14.25
47.0
37.0
89.0
189.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224060 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 12417587 PMID12417587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12417587/
RECORD: Rec_0233859 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
HeLa
100 μM
Concentration response
PMID12417587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12417587/
RECORD: Rec_0317550 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 12417587 PMID12417587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12417587/
RECORD: Rec_0322947 VERIFIED: YES
Provenance & Taxonomy
Bufo bufo [Animal]
Buforin
8384
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Fluorophore labeling
C-term detail: Labelled with Texas Red
Bio-Activity Profile
Cell-penetrating peptide Antimicrobial
HeLa; TM12 cells
Fluorescence-based uptake assay
PMID12417587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12417587/
RECORD: Rec_0385180 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
HeLa
1 μM
Concentration response
PMID12417587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12417587/
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