Peptide Database

Peptide NameSLAY-screened peptide P2536

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC66H97N17O24S

DescriptionStandard

        SGACWDKTDTYQLG
    

Molecular Weight1544.64 Da

Isoelectric Point (pI)4.21

Net Charge (pH 7.0)-1.55

Net Charge (pH 7.4) -1.78

Charge Density (pH 7.0) -0.1107

GRAVY Index-0.82

Hydrophobic Moment 0.11

Boman Index-0.03

Instability Index34.72

Aliphatic Index 35.00

Aromaticity 0.1429

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 682.04

LogP -8.27

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 48.0

Heavy Atoms 108.0

Ring Count 3.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087341 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/