Peptide Database

Peptide NameProthyroliberin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length209 amino acids

Chemical FormulaC1034H1657N333O336S5

DescriptionStandard

        QPLAGEGDPSLDELFQRAESLLIRSILTQTEDENHGDGEQTEWLEKRQHPGKRQHPGKREDTDYEDEAAALQKRQHPGKREEEEDSARLRRQHPGKRLSLEHMMLEEPTAQSELAKRQHPGRRYLMLLHKRQHPGRRELHEAAGDFSDLAKRQHPGKRLCEDWDVTGCDQASILLELLDNVNKSRAEEKRQHPGKRFALEDELTEQESL
    

Molecular Weight24289.57 Da

Isoelectric Point (pI)5.77

Net Charge (pH 7.0)-8.13

Net Charge (pH 7.4) -9.05

Charge Density (pH 7.0) -0.0389

GRAVY Index-1.36

Hydrophobic Moment 0.63

Boman Index-0.36

Instability Index73.85

Aliphatic Index 63.59

Aromaticity 0.0335

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047069 VERIFIED: NO

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyTRH

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGln48 Pyroglutamylation; Pro50 Amidation; Gln54 Pyroglutamylation; Pro56 Amidation; Gln75 Pyroglutamylation; Pro77 Amidation; Gln92 Pyroglutamylation; Pro94 Amidation; Gln118 Pyroglutamylation; Pro120 Amidation; Gln132 Pyroglutamylation; Pro134 Amidation; Gln153 Pyroglutamylation; Pro155 Amidation; Gln191 Pyroglutamylation; Pro193 Amidation

Bio-Activity Profile

Function

Hormone Neuropeptide