Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC433H712N138O140S7

DescriptionStandard

        MRTLAILAAILLFALQAQAESLQETADDAATQEQPGEDDQDLAVSFEENGLSTLRPSGSQPRFRCRCRIGLCSRRESHSGSCLLFGKVGRRCCR
    

Molecular Weight10315.58 Da

Isoelectric Point (pI)6.55

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.33

Hydrophobic Moment 0.85

Boman Index-0.13

Instability Index62.36

Aliphatic Index 79.04

Aromaticity 0.0426

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4534.16

LogP -56.47

H-bond Donors 166.0

H-bond Acceptors 148.0

Rotatable Bonds 350.0

Heavy Atoms 718.0

Ring Count 8.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017724 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence