Peptide Database

Peptide NameOsteostatin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC158H241N43O57

DescriptionStandard

        TRSAWLNSEVAESGLDGDHLSDFSTTSPELYLR
    

Molecular Weight3654.86 Da

Isoelectric Point (pI)4.29

Net Charge (pH 7.0)-4.50

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.1365

GRAVY Index-0.56

Hydrophobic Moment 0.34

Boman Index-0.04

Instability Index60.56

Aliphatic Index 73.94

Aromaticity 0.0909

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1623.19

LogP -20.00

H-bond Donors 58.0

H-bond Acceptors 54.0

Rotatable Bonds 117.0

Heavy Atoms 258.0

Ring Count 6.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048946 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyOsteostatin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0091685 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyOsteostatin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Growth regulation Development regulation Receptor modulation

Targetmammary gland

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0203847 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0269691 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyParathyroid hormone

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone