Peptide Database

Peptide NameFilaggrin-2 (2172-2246)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC311H481N123O121

DescriptionStandard

        TTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSR
    

Molecular Weight7878.90 Da

Isoelectric Point (pI)9.95

Net Charge (pH 7.0)2.28

Net Charge (pH 7.4) 1.57

Charge Density (pH 7.0) 0.0304

GRAVY Index-1.67

Hydrophobic Moment 0.54

Boman Index-0.34

Instability Index60.46

Aliphatic Index 7.87

Aromaticity 0.0267

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3982.60

LogP -74.81

H-bond Donors 146.0

H-bond Acceptors 133.0

Rotatable Bonds 261.0

Heavy Atoms 555.0

Ring Count 13.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050061 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetPseudomonas aeruginosa ATCC 33354[MEC >126.9 microM]

RECORD: Rec_0242658 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEscherichia coli ATCC 11775[MEC >126.9 microM]

RECORD: Rec_0258777 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans ATCC 24433[MEC >126.9 microM]

RECORD: Rec_0381717 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus aureus ATCC 6538[MEC >126.9 microM]