Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC433H681N113O117S9

DescriptionStandard

        MKILCIFLTFFFTVSCGPSVPQKKTREVAEKKRECQLVRGACKPECNSWEYVYYYCNVNPCCVVQEYQKPIINKITSKLHQK
    

Molecular Weight9630.31 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)6.51

Net Charge (pH 7.4) 6.09

Charge Density (pH 7.0) 0.0794

GRAVY Index-0.27

Hydrophobic Moment 0.59

Boman Index-0.04

Instability Index44.13

Aliphatic Index 73.54

Aromaticity 0.1220

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3741.44

LogP -30.65

H-bond Donors 135.0

H-bond Acceptors 134.0

Rotatable Bonds 318.0

Heavy Atoms 672.0

Ring Count 17.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011950 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0339314 VERIFIED: NO