Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length155 amino acids

Chemical FormulaC772H1250N248O237S

DescriptionStandard

        AAQERRKQKENKEKDAKDKLDKESKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKNFDDFRRKFWEEVSKDPELSKQFNPGNKKRLSQGLAPRARNKDTVGGRRSFELHHDKPISQDGGVYDMDNLRITTPKRHIDIHRGQ
    

Molecular Weight17829.77 Da

Isoelectric Point (pI)9.86

Net Charge (pH 7.0)12.16

Net Charge (pH 7.4) 11.71

Charge Density (pH 7.0) 0.0785

GRAVY Index-1.57

Hydrophobic Moment 0.71

Boman Index-0.45

Instability Index48.79

Aliphatic Index 48.52

Aromaticity 0.0581

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8038.24

LogP -91.09

H-bond Donors 276.0

H-bond Acceptors 254.0

Rotatable Bonds 629.0

Heavy Atoms 1258.0

Ring Count 24.0

Amide Bonds 167.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0160825 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Hydrolase Non-hemolytic Non-ribosomal