Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC217H345N55O77S4

DescriptionStandard

        MENLKFNAVIEDVTDQELDLATGAGAKPGDGWISTITDDCPNSIIVCC
    

Molecular Weight5084.64 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.52

Net Charge (pH 7.4) -7.79

Charge Density (pH 7.0) -0.1566

GRAVY Index0.05

Hydrophobic Moment 0.50

Boman Index0.15

Instability Index21.37

Aliphatic Index 91.46

Aromaticity 0.0417

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2110.71

LogP -23.25

H-bond Donors 72.0

H-bond Acceptors 74.0

Rotatable Bonds 166.0

Heavy Atoms 353.0

Ring Count 5.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0275920 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus solimangrovi [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria