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MYP_128712
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Basic Information
NA-CATH
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
34 amino acids
C206H334N54O38
Standard
Sequence
KRFKKFFKKLKNSVKKRAKKFFKKPKVIGVTFPF
Physicochemical Analysis
4175.19 Da
12.00
14.75
14.52
0.4337
-0.76
0.81
-0.30
17.53
51.47
0.2059
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1551.65
-6.73
55.0
53.0
150.0
298.0
9.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0145526 VERIFIED: YES
Provenance & Taxonomy
Naja atra [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0166160 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0202387 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0226656 VERIFIED: YES
Provenance & Taxonomy
Naja atra [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa ATCC BAA-2110
10 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0245505 VERIFIED: YES
Provenance & Taxonomy
Naja atra [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ATCC 51659
21 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
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