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MYP_128712
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Basic Information
NA-CATH
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
34 amino acids
C206H334N54O38
Standard
Sequence
KRFKKFFKKLKNSVKKRAKKFFKKPKVIGVTFPF
Physicochemical Analysis
4175.19 Da
12.00
14.75
14.52
0.4337
-0.76
0.81
-0.30
17.53
51.47
0.2059
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1551.65
-6.73
55.0
53.0
150.0
298.0
9.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016011 VERIFIED: YES
Provenance & Taxonomy
Naja atra [Animal]
Cathelicidin
8656;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus ATCC 25923
0.24 μM
OD600
PaperSnake Cathelicidin NA-CATH and Smaller Helical Antimicrobial Peptides Are Effective against Burkholderia thailandensis PMID26196513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26196513/
RECORD: Rec_0025267 VERIFIED: YES
Provenance & Taxonomy
Naja atra [Animal]
Cathelicidin
8656;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Burkholderia thailandensis E264/ATCC 700388
11.98 μM
OD600; Crystal violet assay
PaperSnake Cathelicidin NA-CATH and Smaller Helical Antimicrobial Peptides Are Effective against Burkholderia thailandensis PMID26196513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26196513/
RECORD: Rec_0029076 VERIFIED: YES
Provenance & Taxonomy
Naja atra [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae ATCC 33495
5.2 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0048507 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
0.37 μM
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/20399752/ PMID20399752 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20399752/
RECORD: Rec_0055253 VERIFIED: YES
Provenance & Taxonomy
Naja atra [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii ATCC BAA-1794
10 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
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