Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length316 amino acids

Chemical FormulaC1530H2439N409O437S12

DescriptionStandard

        KGKDRKREGITMLGGTRRPLPGPRRGRALTPARCPPAPVLVENIYIKIQLGLGSDALGKPTIDTSSCSTRISSIRVTLSGFLCRWLYNLFHKAIESRFRKILESKVCEIVAKSVRSELQPYAQTLPVTAKIDAMAGIDYSLVAPPAATAQSLDVDLKGEFFSLAHRSAVPFPPLALALPPDHDRMVYFGASSYFFNTASVAYHAAGALVLDITNSVIPKDVEFHLNTSTFSAFVPQLEELYPHMEMKVRLSTPSAPFLTIGPDGLSLRPVVDIQTYAILPNSTLAPLFLLSLVSCDCGSVGAAQGAPTASAAAVCP
    

Molecular Weight33939.99 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)6.24

Net Charge (pH 7.4) 5.57

Charge Density (pH 7.0) 0.0197

GRAVY Index0.16

Hydrophobic Moment 0.70

Boman Index0.13

Instability Index47.43

Aliphatic Index 96.68

Aromaticity 0.0759

Extinction Coeff. Reduced 18910.00

Extinction Coeff. Oxidized 19285.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354703 VERIFIED: NO

Provenance & Taxonomy

OrganismMelopsittacus undulatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence