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MYP_128672
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Basic Information
Gaegurin 6 (1, 6-24), GGN6 (1, 6-24)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C102H161N23O25S2
Standard
Sequence
FAGLAANFLPTIICKISYKC
Physicochemical Analysis
2173.64 Da
8.86
1.74
1.50
0.0869
1.05
0.50
0.40
7.37
112.50
0.1500
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
763.25
-4.16
28.0
29.0
68.0
152.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0337140 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human embryonic kidney HEK293T cells
>100 μg/mL
IC50
PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
RECORD: Rec_0352390 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli DH5alpha
100 μg/mL
MIC
PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
RECORD: Rec_0373464 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 14499271 PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
RECORD: Rec_0386442 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
A549
100 μg/mL
IC50
PaperPubMed PMID: 14499271 PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
RECORD: Rec_0426903 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HEK293
100 μg/mL
IC50
PaperPubMed PMID: 14499271 PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
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