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MYP_128672
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Basic Information
Gaegurin 6 (1, 6-24), GGN6 (1, 6-24)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C102H161N23O25S2
Standard
Sequence
FAGLAANFLPTIICKISYKC
Physicochemical Analysis
2173.64 Da
8.86
1.74
1.50
0.0869
1.05
0.50
0.40
7.37
112.50
0.1500
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
763.25
-4.16
28.0
29.0
68.0
152.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0297566 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human lung carcinoma A549
100 μg/mL
IC50
PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
RECORD: Rec_0306353 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC 10031
100 μg/mL
MIC
PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
RECORD: Rec_0308538 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Hep 3B
100 μg/mL
IC50
PaperPubMed PMID: 14499271 PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
RECORD: Rec_0319995 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
14-20
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0325855 VERIFIED: YES
Provenance & Taxonomy
Glandirana rugosa [Animal]
Gaegurin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
14-20
Bio-Activity Profile
Anticancer Cytotoxic
A-549
>100 μg/mL
IC50
PaperIn vitro activities of native and designed peptide antibiotics against drug sensitive and resistant tumor cell lines PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
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