Peptide Database

Peptide NameSakacin P/ Sakacin 674

Function Ontology

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Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC98H145N23O27S2

DescriptionStandard

        KYYGNGVYCTKIKCTVDW
    

Molecular Weight2141.47 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.49

Charge Density (pH 7.0) 0.0964

GRAVY Index-0.43

Hydrophobic Moment 0.29

Boman Index0.02

Instability Index12.77

Aliphatic Index 53.89

Aromaticity 0.2222

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 833.41

LogP -5.81

H-bond Donors 32.0

H-bond Acceptors 31.0

Rotatable Bonds 67.0

Heavy Atoms 150.0

Ring Count 5.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294378 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)