MYP_128577
MDN-0066-beta
Antimicrobial
Standard
8 amino acids
C41H74N8O13
Standard
LETLLSLV
887.07 Da
4.05
-1.24
-1.44
-0.1546
1.80
0.50
0.54
8.75
231.25
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
344.78
-1.13
12.0
12.0
29.0
62.0
0.0
7.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0070283
VERIFIED: YES
Provenance & Taxonomy
Pseudomonas moraviensis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
APD analysis reveals this sequence is most similar (87.5%) to MDN-0066 L:50%. Chemical modification: C-terminal carboxylic acid forms an ester bond with the side chain Oh of T3. C10 fatty acid CHAIN to L1. In addition, E2, allo-T3, L4, L5, and S6 are D-amino acids. The incorporation of valine at position 8 may be due to the richness of valine in the medium
Bio-Activity Profile
Antimicrobial
fungus C-albicans CMCC98001
>25 μg/disc
MIC
RECORD: Rec_0082992
VERIFIED: YES
Provenance & Taxonomy
Pseudomonas moraviensis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
APD analysis reveals this sequence is most similar (87.5%) to MDN-0066 L:50%. Chemical modification: C-terminal carboxylic acid forms an ester bond with the side chain Oh of T3. C10 fatty acid CHAIN to L1. In addition, E2, allo-T3, L4, L5, and S6 are D-amino acids. The incorporation of valine at position 8 may be due to the richness of valine in the medium
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus CMCC26003
2.5 μg/disc
MIC
RECORD: Rec_0128275
VERIFIED: YES
Provenance & Taxonomy
Pseudomonas moraviensis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
APD analysis reveals this sequence is most similar (87.5%) to MDN-0066 L:50%. Chemical modification: C-terminal carboxylic acid forms an ester bond with the side chain Oh of T3. C10 fatty acid CHAIN to L1. In addition, E2, allo-T3, L4, L5, and S6 are D-amino acids. The incorporation of valine at position 8 may be due to the richness of valine in the medium
Bio-Activity Profile
Antimicrobial
P-aeruginosa CMCC10104
>25 μg/disc
MIC
RECORD: Rec_0419014
VERIFIED: YES
Provenance & Taxonomy
Pseudomonas moraviensis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
APD analysis reveals this sequence is most similar (87.5%) to MDN-0066 L:50%. Chemical modification: C-terminal carboxylic acid forms an ester bond with the side chain Oh of T3. C10 fatty acid CHAIN to L1. In addition, E2, allo-T3, L4, L5, and S6 are D-amino acids. The incorporation of valine at position 8 may be due to the richness of valine in the medium
Bio-Activity Profile
Antimicrobial
B-subtilis CMCC63501
>25 μg/disc
MIC