Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length466 amino acids

Chemical FormulaC2328H3696N610O668S16

DescriptionStandard

        MRQSEVKLMTKNFPSYPHCRRIGMELVKQAVLKETFPSWSGQESLSVVKVNYVISRLRINAVDFPETSASFIPGTGICLSVARASATISADWRMNAWLLKGKGEITVSISGLFISIIFNVSRDSTGHLSTLLHNCQLSIGSVKVKLSGRSSWIYSFLSGYLEKPIHTKLDKNLCLNIKYKIQMMDAQLKKHKVLSQIDTFAQVDYSLLSSPAVFKSHINLDLKGTVYPVGNHTDPPFMPAPFALPNQGDSMIYLGVSNYFLKSASLAYYRAGAFNITISEELATTFSLNTSLLKYFVSETSLSQAAACPVLLNLMATLPPAVSLNADRCVLQITGSVEVFAALPNSTTQYIFTGNLTASTTANLTITKQKLIISLLLKRFQFSLLHSNLGFPEQKSVVENFLSYALRRVVIPVINDKLGKGFPLLNLAHTSLTGPAIKMNQGHLVISTDVHYQPVDREDEDLHSHS
    

Molecular Weight51430.97 Da

Isoelectric Point (pI)9.29

Net Charge (pH 7.0)12.59

Net Charge (pH 7.4) 11.53

Charge Density (pH 7.0) 0.0270

GRAVY Index0.10

Hydrophobic Moment 0.63

Boman Index0.13

Instability Index34.83

Aliphatic Index 101.67

Aromaticity 0.0880

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44725.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0142798 VERIFIED: NO

Provenance & Taxonomy

OrganismLepidothrix coronata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria