Peptide Database

Peptide NameAla57 substitution mutant of Tat (49-57)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC50H99N27O11

DescriptionStandard

        RKKRRQRRA
    

Molecular Weight1254.50 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.7509

GRAVY Index-3.56

Hydrophobic Moment 0.58

Boman Index-1.76

Instability Index193.80

Aliphatic Index 11.11

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 700.75

LogP -8.86

H-bond Donors 28.0

H-bond Acceptors 18.0

Rotatable Bonds 48.0

Heavy Atoms 88.0

Ring Count 0.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400730 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Termfluorescein with 6-aminohexanoic acid (Ahx) spacer

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

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