Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC989H1563N269O264S9

DescriptionStandard

        PMTPPVAHEPMLLLAVTEFVANSAASTYFTAGALRRNISSDMLPRRFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELAWTPLPVLCWAQGLPVPQVKRLETLLKFVLWLFGVPRANSKCCPHAVP
    

Molecular Weight21734.22 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)5.38

Net Charge (pH 7.4) 4.98

Charge Density (pH 7.0) 0.0274

GRAVY Index0.06

Hydrophobic Moment 0.60

Boman Index0.11

Instability Index55.16

Aliphatic Index 96.53

Aromaticity 0.0765

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8329.04

LogP -99.98

H-bond Donors 286.0

H-bond Acceptors 283.0

Rotatable Bonds 676.0

Heavy Atoms 1531.0

Ring Count 47.0

Amide Bonds 210.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239574 VERIFIED: NO

Provenance & Taxonomy

OrganismPolioptila caerulea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria