Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length395 amino acids

Chemical FormulaC1985H3119N523O554S11

DescriptionStandard

        NPGFMVRITQAGLDYAHLQGITILEKELTHVKLPDISGDFRIRHVGKVHYEFSRLDLRGFHLPYSRISLVPKVGLQVSIASAFADVDGNWRVKIHFLRDHGSFEVSVENVYIKINLKLGNDASGKPTIDTSDCSTRISKVRVRFSGRLGWLYNLFHSAIESRFRKILEGKVCDIVVKSVHSDLQPYVQTLPVTTKIDAVAGVDYSLVAPPTATAQSLDVAMKGECYFLAQRSAVPFAPLALTLPPDHDRMVYFGASSYFFNTASFAYHEAGALVFEITDSMIPKTIDFHLNTTTFSAFVPQLEKMYPDMKMKLRLSAPSAPFLSIGPGGLSLKPVVDIQAYAILPNSSLAPLFLISLVSNVSAVINVKSGHIIGNLTVGRMKLSLKHSDVGTFQV
    

Molecular Weight43526.88 Da

Isoelectric Point (pI)9.14

Net Charge (pH 7.0)7.97

Net Charge (pH 7.4) 6.93

Charge Density (pH 7.0) 0.0202

GRAVY Index0.14

Hydrophobic Moment 0.65

Boman Index0.13

Instability Index29.82

Aliphatic Index 100.66

Aromaticity 0.0962

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415797 VERIFIED: NO

Provenance & Taxonomy

OrganismJacana jacana (Wattled jacana) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria