Peptide Database

Peptide NameReptilian Defensin

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antiviral

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC177H296N52O46S6

DescriptionStandard

        EKKCPGRCTLKCGKHERPTLPYNCGKYICCVPVKVK
    

Molecular Weight4080.95 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)6.86

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.1905

GRAVY Index-0.61

Hydrophobic Moment 0.52

Boman Index-0.21

Instability Index31.60

Aliphatic Index 56.67

Aromaticity 0.0556

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1579.89

LogP -14.37

H-bond Donors 60.0

H-bond Acceptors 60.0

Rotatable Bonds 134.0

Heavy Atoms 281.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305036 VERIFIED: YES

Provenance & Taxonomy

OrganismCaretta caretta [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral

TargetChandipura virus

RECORD: Rec_0329546 VERIFIED: YES

Provenance & Taxonomy

OrganismCaretta caretta [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral

TargetSalmonella typhimurium

Activity2.8 μM

MethodIC50

RECORD: Rec_0370594 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

RECORD: Rec_0417626 VERIFIED: YES

Provenance & Taxonomy

OrganismCaretta caretta [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral

TargetEscherichia coli

Activity2.3 μM

MethodIC50

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