Peptide Database

Peptide NameYwcI signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC156H257N45O35S3

DescriptionStandard

        MKRLLVSLRVWMVFLMNWVTPDRKTARA
    

Molecular Weight3419.18 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.50

Net Charge (pH 7.4) 4.28

Charge Density (pH 7.0) 0.1607

GRAVY Index0.20

Hydrophobic Moment 0.51

Boman Index-0.02

Instability Index21.47

Aliphatic Index 104.29

Aromaticity 0.1071

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1312.53

LogP -6.79

H-bond Donors 49.0

H-bond Acceptors 43.0

Rotatable Bonds 112.0

Heavy Atoms 239.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0410653 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

Activity0.0 U/mL

MethodCutinase activity assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/