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MYP_128457
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Basic Information
Hylin-b2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
19 amino acids
C88H149N23O21
Standard
Sequence
FIGAILPAIAGLVGGLINR
Physicochemical Analysis
1865.27 Da
9.75
0.76
0.56
0.0400
1.61
0.43
0.61
37.44
174.74
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
683.32
-3.42
23.0
22.0
59.0
132.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015188 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas lundii [Animal]
Hylin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/P84003/entry
RECORD: Rec_0025425 VERIFIED: YES
Provenance & Taxonomy
Hyla biobeba [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Hemolytic
PaperPubMed PMID: 15638808 PMID15638808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15638808/
RECORD: Rec_0030660 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0073145 VERIFIED: YES
Provenance & Taxonomy
Hyla biobeba [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 15638808 PMID15638808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15638808/
RECORD: Rec_0103667 VERIFIED: YES
Provenance & Taxonomy
Hyla biobeba or [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
-
PaperHylins: bombinins H structurally related peptides from the skin secretion of the Brazilian tree-frog Hyla biobeba.
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