Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC378H600N110O108S10

DescriptionStandard

        MAKFASIVALLFAALVLLASLEAPTMVEAQKLCERSSGTRSGVCGNNNACKNQCINLEGARHGSCNYRFPYHRCICYFPC
    

Molecular Weight8734.13 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)3.60

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.0450

GRAVY Index0.18

Hydrophobic Moment 0.52

Boman Index0.08

Instability Index34.01

Aliphatic Index 80.62

Aromaticity 0.0875

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3497.22

LogP -37.94

H-bond Donors 129.0

H-bond Acceptors 124.0

Rotatable Bonds 284.0

Heavy Atoms 606.0

Ring Count 12.0

Amide Bonds 87.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0130101 VERIFIED: NO

Provenance & Taxonomy

OrganismRorippa indica [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence