Peptide Database

Peptide NameDefensin anti-microbial peptide (Defensin-A)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC452H714N132O143S9

DescriptionStandard

        MNSLGTACFAVLCLFAIVSTGNGFPQESADQVQYFANTLFDELPEQSYQAAAENLRLKRATCDLLSGLGVNDSACAAHCIARGNRGGYCNSKKVCVCRN
    

Molecular Weight10573.89 Da

Isoelectric Point (pI)6.51

Net Charge (pH 7.0)-0.48

Net Charge (pH 7.4) -0.88

Charge Density (pH 7.0) -0.0049

GRAVY Index0.02

Hydrophobic Moment 0.61

Boman Index0.06

Instability Index36.51

Aliphatic Index 77.98

Aromaticity 0.0808

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4455.57

LogP -55.20

H-bond Donors 160.0

H-bond Acceptors 153.0

Rotatable Bonds 348.0

Heavy Atoms 736.0

Ring Count 11.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280046 VERIFIED: NO

Provenance & Taxonomy

OrganismCulex quinquefasciatus [Animal]

FamilyDefensin

Tax ID7176

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal