Peptide Database

Peptide NameMaximins y Hw [Cleaved into: Maximin-y

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length142 amino acids

Chemical FormulaC692H1137N197O211S2

DescriptionStandard

        MIFKYIVAVSFLIASGYARSVKNDEQSLSQREVLEEESLREIRGIGGALLSVGKSALKGLAKGFAEHFGKRTAEDHEVMKRLEAVIRDLDSLDHSEEASERETRGFNQEEIANLFTKKEKRILGPVLGLVSNAIGGLIKKIG
    

Molecular Weight15656.75 Da

Isoelectric Point (pI)6.86

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.62

Charge Density (pH 7.0) -0.0014

GRAVY Index-0.24

Hydrophobic Moment 0.71

Boman Index-0.03

Instability Index41.80

Aliphatic Index 100.99

Aromaticity 0.0563

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6641.05

LogP -64.15

H-bond Donors 233.0

H-bond Acceptors 216.0

Rotatable Bonds 554.0

Heavy Atoms 1102.0

Ring Count 12.0

Amide Bonds 148.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0331306 VERIFIED: NO

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Cytolytic Hemolytic Non-ribosomal

MethodQualitative functional evidence