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MYP_128294
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Basic Information
Beta-defensin 5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
66 amino acids
C322H518N92O87S8
Standard
Sequence
MQILPLLFAVLLLMLQAEPGLSLARGLPQDCERRGGFCSHKSCPPGIGRIGLCSKEDFCCRSRWYS
Physicochemical Analysis
7326.64 Da
8.66
2.54
2.17
0.0384
0.13
0.64
0.06
72.24
91.67
0.0758
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2836.16
-25.19
105.0
99.0
239.0
509.0
12.0
68.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0136058 VERIFIED: YES
Provenance & Taxonomy
Anas platyrhynchos [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella choleraesuis CVCC 2140
PMID23112840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23112840/
RECORD: Rec_0149394 VERIFIED: YES
Provenance & Taxonomy
Anas platyrhynchos [Animal]
Defensin
8839;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Duck hepatitis virus (Replication); Duck embryo
Neutralization assay
PaperIdentification, expression and activity analyses of five novel duck beta-defensins. | Ma D, Zhang K, Zhang M, Xin S, Liu X, Han Z, Shao Y, Liu S. | PLoS One. 2012 | PMID:23112840 PMID23112840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23112840/
RECORD: Rec_0167733 VERIFIED: YES
Provenance & Taxonomy
Anas platyrhynchos [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Lactobacillus ATCC33222
PMID23112840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23112840/
RECORD: Rec_0182677 VERIFIED: YES
Provenance & Taxonomy
Anas platyrhynchos [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella pullorum C79-11-S11
PMID23112840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23112840/
RECORD: Rec_0201322 VERIFIED: YES
Provenance & Taxonomy
Anas platyrhynchos [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pasteurella multocida ATCC 6529
PMID23112840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23112840/
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