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MYP_128280
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Basic Information
Ocellatin-PT6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
32 amino acids
C149H250N42O44S
Standard
Sequence
GVFDIIKGAGKQLIAHAMEKIAEKVGLNKDGN
Physicochemical Analysis
3365.90 Da
8.39
0.85
0.58
0.0266
-0.10
0.59
0.09
4.45
103.75
0.0312
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1402.67
-12.45
46.0
47.0
121.0
236.0
2.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0233348 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania infantum MHOM/MA/67/ITMAP-263
67.51 μg/mL
IC50
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0262510 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania infantum MHOM/MA/67/ITMAP-263
42.62 μg/mL
IC50
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0272282 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiparasitic
S.choleraesuis ATCC 14028
>240 μM
MIC
PaperCharacterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus
RECORD: Rec_0285859 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Pseudomonas aeruginosa ATCC 27853
1024 μg/mL
MIC
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0308492 VERIFIED: YES
Provenance & Taxonomy
Skin Secretion,dorsal,Leptodactylus pustulatus [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
-
PMID26107622;27463422 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
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