Peptide Database

Peptide NameHirudomacin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC288H457N89O90S8

DescriptionStandard

        TPSCYEDWSRCTPGTQFLTGILWKDCNSRCKELGRRGGRCVDSPSKSCPGVLKNNKQCQCY
    

Molecular Weight6862.77 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.32

Net Charge (pH 7.4) 4.00

Charge Density (pH 7.0) 0.0708

GRAVY Index-0.83

Hydrophobic Moment 0.85

Boman Index-0.22

Instability Index63.31

Aliphatic Index 41.48

Aromaticity 0.0820

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2933.14

LogP -38.12

H-bond Donors 111.0

H-bond Acceptors 103.0

Rotatable Bonds 224.0

Heavy Atoms 475.0

Ring Count 11.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407305 VERIFIED: YES

Provenance & Taxonomy

OrganismHirudo nipponica Whitman [Animal]

FamilyMacin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetListeria monocytogenes ATCC 19115

Activity6.25 μg/mL

MethodMBC

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